Purified anti-human CD4 317401 from BioLegend

Product Specs
ItemPurified anti-human CD4
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number317401
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ApplicationsFlow Cytometry (FC), Immunohistochemistry (IHC)-F
Conjugate/TagUnconjugated
IsotypeIgG2b, Kappa
ReactivityHuman, Cynomolgus, Rhesus
HostMouse
Quantity25 µg
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
CloneOKT4
NCBI Full Gene NameCD4 molecule
Concentration0.50 mg/mL
ClonalityMonoclonal
Antibody TypePrimary
ImmunogenHuman peripheral T cells
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Cell type-specific delivery by modular envelope designNat CommunAugust 23, 2023Daniel Strebinger, Chris J. Frangieh, Mirco J. Friedrich, Guilhem Faure, Rhiannon K. Macrae, Feng Zhangthe high number of surface exposed lysines. αCD3 (BioLegend Cat. # 317302), αCD4 (BioLegend Cat. # 317402) and αCD19 (BioLegend Cat. # 302202) were each labeled with a 40-fold molar excess of NHS-GLA-BG. αCD28

(2) Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19Cell reports. MedicineJuly 19, 2022Feyaerts D, Hédou J, Gillard J, Chen H, Tsai ES, Peterson LS, Ando K, Manohar M, Do E, Dhondalay GKR, et al.CD38 (clone HIT2),BioLegend,Cat# 303502; RRID: AB_314354 Anti-human CD4 (clone OKT4),BioLegend,Cat# 317402; RRID: AB_571963 Anti-human CD45 (clone HI30),BioLegend,Cat# 304002; RRID: AB_314390 Anti-human CD45RA

(3) Human influenza virus challenge identifies cellular correlates of protection for oral vaccinationCell Host & MicrobeDecember 1, 2021David R. McIlwain, Han Chen, Zainab Rahil, Neda Hajiakhoond Bidoki, Sizun Jiang, Zach Bjornson, Nikita S. Kolhatkar, C. Josefina Martinez, Brice Gaudillière, Julien Hedou, et al.Anti-CD8,Biolegend,"Biolegend Cat#301053, RRID:AB_2562810" Mouse Monoclonal Anti-CD4,Biolegend,"Biolegend Cat#317402, RRID:AB_571963" Mouse Monoclonal Anti-CD3,BD Biosciences,"BD Biosciences Cat#551916, RRID:AB_394293" Mouse

(4) AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammationMolecular Therapy - Methods & Clinical DevelopmentMarch 12, 2021Gwladys Gernoux, MickaÃ«l Guilbaud, Marie Devaux, Malo Journou, Virginie Pichard, Nicolas Jaulin, Adrien LÃ©ger, Johanne Le Duff, Jack-Yves Deschamps, Caroline Le Guiner, et al.GFP+ cells and Tregs. Polyclonal rabbit anti-human CD3 (A0452; Dako), monoclonal mouse anti-human CD4 (317402; BioLegend), and monoclonal rat anti-human CD8 (MCA351GT; Serotec) antibodies were used to detect CD4

(5) Early drop of circulating T cells negatively correlates with the protective immune response to Yellow Fever vaccinationHuman Vaccines & ImmunotherapeuticsDecember 1, 2020Amandine Bovay, Daniel E. Speiser, Silvia A. Fuertes Marraco

(6) Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in PsoriasisImmunityJuly 14, 2020Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, Liu Z, Zhou H, Bai J, Yin Q, et al.

(7) Bispecific antibodies enhance tumor-infiltrating T cell cytotoxicity against autologous HER-2-expressing high-grade ovarian tumorsJournal of leukocyte biologyJune 1, 2020Oberg HH, Janitschke L, Sulaj V, Weimer J, Gonnermann D, Hedemann N, Arnold N, Kabelitz D, Peipp M, Bauerschlag D, et al.

(8) ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to ActivationCell reportsMarch 10, 2020Ghosh S, Di Bartolo V, Tubul L, Shimoni E, Kartvelishvily E, Dadosh T, Feigelson SW, Alon R, Alcover A, Haran G.

(9) Muscle-Directed Delivery of an AAV1 Vector Leads to Capsid-Specific T Cell Exhaustion in Nonhuman Primates and HumansMolecular therapy : the journal of the American Society of Gene TherapyMarch 4, 2020Gernoux G, Gruntman AM, Blackwood M, Zieger M, Flotte TR, Mueller C.Polyclonal rabbit anti-human CD3 (1:100) (A0452, Dako), monoclonal mouse anti-human CD4 human (1:100) (317402, BioLegend), monoclonal rat anti-human CD8 (1:100) (MCA351GT, Bio-Rad), monoclonal mouse anti-human FoxP3

(10) Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV NeutralizationCellJuly 25, 2019Kong R, Duan H, Sheng Z, Xu K, Acharya P, Chen X, Cheng C, Dingens AS, Gorman J, Sastry M, et al.

(11) Group 3 innate lymphoid cells mediate early protective immunity against tuberculosisNatureJune 1, 2019Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, et al.

(12) The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expressioneLifeApril 30, 2019Fletcher-Jones A, Hildick KL, Evans AJ, Nakamura Y, Wilkinson KA, Henley JM.RRID:AB_10673030,ICC (1:500) Antibody,anti-CD4 (mouse monoclonal; purified; clone OKT4),BioLegend,BioLegend:317402; RRID:AB_571963,ICC (1:400) Antibody,anti-MAP2 (rabbit polyclonal),Synaptic Systems,SySy:188 003; RRID:AB_2281442,ICC

(13) Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8⁺ T CellsFrontiers in immunologyJanuary 1, 2019Li Y, Teteloshvili N, Tan S, Rao S, Han A, Yang YG, Creusot RJ.

(14) Generation of Hutat2:Fc Knockin Primary Human Monocytes Using CRISPR/Cas9Molecular therapy. Nucleic acidsJune 1, 2018Wang B, Zuo J, Kang W, Wei Q, Li J, Wang C, Liu Z, Lu Y, Zhuang Y, Dang B, et al.

(15) CISH promoter polymorphism effects on T cell cytokine receptor signaling and type 1 diabetes susceptibilityMolecular and cellular pediatricsFebruary 6, 2018Seyfarth J, Ahlert H, Rosenbauer J, Baechle C, Roden M, Holl RW, Mayatepek E, Meissner T, Jacobsen M.

(16) Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individualsVirologyFebruary 1, 2018Prévost J, Richard J, Ding S, Pacheco B, Charlebois R, Hahn BH, Kaufmann DE, Finzi A.

(17) STAT5B: A Differential Regulator of the Life and Death of CD4⁺ Effector Memory T CellsJournal of immunology (Baltimore, Md. : 1950)January 1, 2018Majri SS, Fritz JM, Villarino AV, Zheng L, Kanellopoulou C, Chaigne-Delalande B, Grönholm J, Niemela JE, Afzali B, Biancalana M, et al.

(18) Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory ResponsesmSphereJanuary 1, 2018Brinkmann CR, Højen JF, Rasmussen TA, Kjær AS, Olesen R, Denton PW, Østergaard L, Ouyang Z, Lichterfeld M, Yu X, et al.

(19) Fecal bacteria from treatment-naive Crohn's disease patients can skew helper T cell responsesExperimental cell researchDecember 1, 2017Ma F, Zhang Y, Xing J, Song X, Huang L, Weng H, Wu X, Walker E, Wang Z.

(20) Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytesNature communicationsNovember 22, 2017Santos RLA, Bai L, Singh PK, Murakami N, Fan H, Zhan W, Zhu Y, Jiang X, Zhang K, Assker JP, et al.

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Purified anti-human CD4 from BioLegend

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Purified anti-human CD4 from BioLegend

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